HopCellTM human iPSC/ESC-Derived 3D cerebral brain organoids are highly homogenous in size, region identities, cell components and structures, etc. They can be kept in long time culture up to 350 days. The cortical organoids stably express typical layer-specific markers, such as CITP2, SATB2, BRN2, Reelin.
3D brain organoids (Day17 after plating)
3D brain organoids in Matrigel (Day 132 after plating)
CTIP2(Green) Reelin (Red) DAPI(Blue) (Day 99)
BRN2(Green) SATB2 (Red) DAPI(Blue) (Day 99)